案件查詢
| 計畫編碼 | 計畫主持人 | 研究護理師 | 癌別 | 計畫名稱 | 收案條件 | 藥物 | 附件檔 |
| D8990C00001 | 鍾奇峰 | 翁湘芸#1677 吳星慧#1676 | 其他 | 一項模組化第 I／IIa 期、開放性、多中心試驗，評估 AZD5335 遞增劑量單一療法與合併抗癌藥物使用於實體腫瘤參與者的安全性、耐受性、藥動學和初步療效 | Ovarian Cancer Lung cancer |
AZD5335 AZD5335 +AZD5305 | 下載 |
| D8991C00001 | 鍾奇峰 | 楊琇帆#1689馮晴＃1670 | 婦癌 | 一項隨機、開放標籤 III 期研究，比較 AZD5335 與 Mirvetuximab Soravtansine 在 FRα-high 中的療效以及 AZD5335 與醫師選擇化療上皮性卵巢癌患者中的療效 (TREVI-OC-01) | 1.high-grade serous EOC, primary peritoneal cancer, or fallopian tube cancer. 2. must have platinum-resistant disease: (a) Participants who have only had one prior line of platinum-based therapy must have received at least 4 cycles of platinum, must have had a response (CR or PR) and then progressed between > 3 months and ? 6 months after the date of the last dose of platinum. (b) Participants who have received 2 or 3 lines of platinum therapy must have progressed ? 6 months after the date of the last dose of platinum. 3. must have received at least one, but no more than 3, prior systemic lines of anti-cancer therapy |
AZD5335 | 下載 |
| DS7300-203 | 鍾奇峰 | 張雅雯#1687 | 其他 | 一項第 1b／2 期、泛腫瘤、開放標記試驗，旨在評估 Ifinatamab Deruxtecan (I-DXd) 用於復發性或轉移性固體腫瘤受試者的療效及安全性 (IDeate-Pantumor02) | Pathologically or cytologically documented unresectable or metastatic UC of the bladder, renal pelvis, ureter, or urethra. Subjects with histological variants are allowed if urothelial histology is predominant. Small cell/neuroendocrine tumors are not allowed even if mixed histology |
Ifinaatamab Deruxtecan (I-DXd) | 下載 |
| DS8201-793 | 陳鵬宇 | 楊琇帆#1689 | 肺癌 | 一項第 3 期、多中心、隨機分配、開放標示，在患有局部晚期無法切除或轉移性 HER2 過度表現和 PD-L1 TPS <50% 非鱗狀非小細胞肺癌之參與者，評估 Trastuzumab Deruxtecan 併用 Pembrolizumab 相較於鉑類化療併用 Pembrolizumab 作為第一線療法的試驗 (DESTINY-Lung06) | 非麟狀局部晚期無法切除 轉移性NSCLC |
Trastuzumab Deruxtecan (T-DXd; Enhertu) | 下載 |
| DS8201-801 | 鍾奇峰 | 莊淑敏#1673 | 乳癌 | 這是一項皮下注射 T-DXd 加上玻尿酸的第 1 期、開放性、多中心、劑量調升和劑量擴展試驗，旨在評估 SC T-DXd 加上玻尿酸在轉移性實體腫瘤參與者中的安全性、耐受性、PK 和療效 | Participants ‧ HER2+, HER2low as per FDA-approved T-DXd indication ‧ locally advanced/metastatic cancer ‧ No previous history of T-DXd use |
T-DXd | 下載 |